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CROSPOVIDONE USP / EP /BP / IP :s |
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International non-proprietary name ( INN) : Crospovidone |
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Chemical Name : Cross-linked homopolymer of 1-ethenylpyrrolidin-2-one |
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Other non-proprietary name : PVPP; Insoluble PVP; Crospovidonum; Polyvinylpolypyrrolidone
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Cas No : [25249-54-1] |
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Molecular Formula :
(C 6H 9NO) n |
Pharmaceutical Industry : |
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Provide rapid disintegration in a wide range of oral solid dosage formulations and processes.
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Ideally suited for use with poorly compressible drug actives and in direct compression tablet processes.
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Outstanding performance in manufacturing ionic, acidic and alkaline drug actives.
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Quick dissolve and chewable tablets.
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Treat gastrointestinal disorders and as an anti-diarrhea agent.
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Can also be used to improve solubility, and hence, enhance bioavailability in not only human but also veterinary applications.
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PVP-P can be used in
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Improving the quality and extends the shelf-life of beer by absorbing the polyphenyls and tannoids.
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Prevention of 'pinking' and 'browning' reactions in white and sparkling wines.
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Enhanced aroma and flavor in red wines.
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cost-effective and safe treatment in beer industry that.
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Completely insoluble in beer.
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Applicable to all types of beer.
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Higher efficacy - lower dosage.
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Easy to use and excellent handling characteristics.
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Insoluble process aids, with wide regulatory approval.
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No negative impact on foam, flavor or other quality parameters.
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Improved dispersion and sedimentation characteristics.
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Longer filter run lengths compared to silica alone.
- Uses existing plant equipment.
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ANALYTICAL SPECIFICATION OF CROSPOVIDONE USP / EP / BP / IP : |
TEST |
STANDARDS |
APPEARANCE
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A White to yellowish white powder
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IDENTIFICATION : A + B + C + D
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Positive
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PH VALUE |
5.0 to 8.0 |
PEROXIDE,
AS H2O2 |
NMT 400 ppm |
WATER SOLUBLE SUBSTANCES |
NMT 1.0% |
VINYLPYRROLIDONE |
NMT 10 ppm |
HEAVY METALS |
NMT 10 ppm |
WATER |
NMT 5.0 % |
LOSS ON DRYING |
NMT 5.0% |
SULPHATED ASH |
NMT 0.1% |
NITROGEN CONTENT (ASSAY) |
11.0 – 12.8% |
RESIDUAL SOLVENTS |
No class I, class II & class III solvents are present in this product as listed in the current USP <467>
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CROSPOVIDONE USP / EP /BP / IP |
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